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Is semaglutide or tirzepatide better for Hashimoto's patients

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doi: 10.1530/EDM-21-0007

Role of -cell Produced Gcg in Insulin Secretion -Cell GLP-1 during metabolic stress PC1/3, which processes GLP-1 (and GLP-2 and oxyntomodulin) from Gcg , is more predominantly expressed in the gut and CNS, but -cell PC1/3 activity and/or expression is found in embryonic and neonatal mice, with pregnancy, and in models of prediabetes and diabetes (118, 172, 224, 245)

Oral semaglutide 50 mg taken once per day in adults with overweight or obesity (OASIS 1): a randomised, double-blind, placebo-controlled, phase 3 trial One randomized, double-blind, placebo-controlled trial evaluated the safety and effectiveness of oral semaglutide (GLP-1) 50 mg, taken once daily in adults with overweight or obesity who did not have type 2 diabetes