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Research consistently shows that preserving strength during a cut is one of the best predictors of muscle retention

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For individuals managing type 2 diabetes, maintaining a healthy weight is often an essential part of their overall care plan, making Metformins weight-neutral or modest weight loss effect a welcome bonus

Serious adverse effects include hypertension, immunosuppression, gastrointestinal ulceration, glucose instability, and osteoporosis

In September 2025 , Novo announced plans to eliminate 9,000 roles globally (about 11% of its workforce) to improve agility and redirect capital toward higher-growth areas