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Electrolytes like sodium help maintain proper blood pressure and circulation

SNRIs like venlafaxine and duloxetine have a similar profile, with duloxetine also licensed for diabetic neuropathic pain

During pregnancy, insulin resistance typically increases, necessitating higher insulin production to maintain normal blood sugar levels

Metabolite pathway sets were downloaded from the Small Molecule Pathway Database (SMPDB) (71), and metabolite set enrichment was tested using the limma ROAST method (72)

Therefore, high serum B12 levels in individuals supplementing with B12 are typically harmless and do not cause adverse health effects