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Drinking or eating less, along with nausea, vomiting, or diarrhea, can all leave you more dehydrated and dry-mouthed

Patients entered a run-in treatment period on glimepiride (greater than or equal to 4 mg per day) alone or glimepiride in combination with metformin (greater than or equal to 1500 mg per day)

Gastrointestinal problems: Common side effects such as nausea, vomiting, and diarrhea may occur more frequently in older adults, according to John Batsis, MD, a geriatric obesity specialist at the University of North Carolina School of Medicine and Global Public Health in Chapel Hill

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Wadden, Ph.D., Sean Wharton, M.D., Pharm.D., Koutaro Yokote, M.D., Ph.D., et al., for the STEP 1 Study Group* 2