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Generic injectable semaglutide could cost as little as $28 per person-year after the initial patent expired in April 2026 a fraction of current branded prices and be available in about 162 countries by the end of 2026, covering roughly 69% of the global type 2 diabetes (T2D) burden and 84% of the clinical obesity burden

Furthermore, too much NO depletes intracellular GSH, making the body more vulnerable to oxidative stress 98

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