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The manufacturers that gain a sustained advantage in PBM negotiations over the next five years will be those that deploy this analytical capability systematically not as a one-time exercise at launch, but as an ongoing commercial intelligence function that monitors formulary changes, competitive developments, and regulatory shifts in real time and translates that monitoring into contract renegotiation triggers

Patients were included if they met all the following criteria: (1) new-onset type 2 diabetes diagnosed between 1 January 2006 and 31 December 2015, according to International Classification of Diseases, Revision 10 (ICD-10) code (Additional file 1: Table S1) or use of antidiabetic medications by the Anatomical Therapeutic Chemical (ATC) classification codes (Additional file 1: Table S2)

A mother experiencing persistent nausea may struggle to eat enough calories regardless of her intentions