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Trial data and post-hoc analyses identify several factors associated with better response: female sex, lower baseline weight, and early weight loss trajectory

They are not approved for human use, medical treatment, or self-administration

Activating brain regions associated with satiety: Semaglutide influences brain areas that control feelings of fullness, helping patients feel satisfied for longer periods, which is crucial for effective weight management

Research links GLP-1 activity to improved cardiovascular function, neuroprotection, and even anti-inflammatory effects that may contribute to healthy aging [12,13]