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283,333 To overcome dormancy-mediated resistance, therapeutic strategies in which CSCs proliferate via CDK4/6 inhibitors 334 or drive differentiation via agents such as all-trans retinoic acid (ATRA) 335 have been explored

Belangrijke Onderzoeksgebieden Structureel Collageensynthese Dynamiek van de extracellulaire matrix Bindweefsel-signalering Epitheliaal Matrixremodellering Weefseldynamiek Follikelsignalering Systemisch Cytokinemodulatie Cellulaire levensvatbaarheid Pathway-dynamiek Samen suggereren deze bevindingen een brede experimentele potentie voor GHK-Cu binnen structurele, epitheliale en systemische pathways

PMID: 2407766