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It supports gamete quality in the months before conception, so its formulation typically includes the folate-and-vitamin-D base that overlaps with a prenatal, plus additional compounds that specifically influence oocyte or sperm biology, most commonly CoQ10, myo-inositol, L-carnitine (in male formulations), and higher doses of antioxidants

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Most clinical improvements appear within 12-26 weeks

However, there may be brief fluctuations during the transition period when tirzepatide is at its starting dose

References Warburg, O