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The analysis duration was 60 min, the electrospray voltage was set at 2.1 kV, and the detection mode was positive ionization

For optimal absorption, consider administering injections in the evening and rotating injection sites to enhance comfort

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39 As shown in the LEADER study (NCT01179048), the secondary composite outcome of persistent doubling of the serum creatinine level, new-onset persistent macroalbuminuria, end-stage renal disease or death due to renal disease occurred significantly less frequently in the treatment group than in the placebo group, with a hazard ratio of 0.78