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To achieve blood levels of at least 30 ng/mL, adults living at temperate latitudes (think: anywhere with distinct seasons) need 800 to 1,000 IU per day, ideally from vitamin D3, which is more effective than D2

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Pancreatic Insufficiency: The pancreas helps with B12 absorption, and not enough of it can cause deficiency

Both compounds are predominantly renally excreted with 29% of methylene blue and 26% of hydroxocobalamin excreted at 24 h post-administration [9, 10]