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Side Effects and Safety Considerations Like all medications, semaglutide comes with potential side effects, the most common of which are gastrointestinal issues such as nausea, vomiting, and diarrhea

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Among the most important are the degeneration of dopaminergic neurons and the loss of the substantia nigra, combined with the intracellular aggregation of -synuclein, which forms Lewy bodies and neurites [7]