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[9] Whilst these effects support glycaemic control and weight reduction, they also present a nutritional challenge: reduced food intake can inadvertently lead to inadequate protein consumption

Due to this cleavage by DPP-4, GLP-1 (7-36) amide has a very short half-life in vivo between 1 2 minutes 6,7 , which reduces the biological effects of active GLP-1 (7-36) amide 5

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For most people, this simply means including a solid protein source at each meal

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