Furthermore, when we repeated the meta-analysis excluding ELIXA, the trial done with a short-acting GLP-1 receptor agonist in patients with acute coronary syndrome, the outcome of worsening of kidney function, based predominantly on change in eGFR, was also improved. Sattar and colleagues analyzed data from eight randomized, placebo-controlled trials with 60,080 participants testing injectable or oral GLP-1 receptor agonists in adults with type 2 diabetes, including the recently presented AMPLITUDE-O
Many patients prescribed Mounjaro (tirzepatide) for type 2 diabetes or weight management wonder whether lifelong treatment is necessary
The body does most tissue repair during sleep, making evening dosing physiologically advantageous
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This article outlines the place of GLP-1 and GIP analogues in wider therapy, while also highlighting relevant cautions, contraindications and side effects, with the aim of supporting safe prescribing and use of GLP-1 and GIP analogues for glycaemic control in adults with T2DM
