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Record-Breaking Weight Loss Outcomes In the Phase 3 TRIUMPH-4 study, retatrutide demonstrated unprecedented weight-loss efficacy among adults with obesity and knee osteoarthritis: 23.7% average weight loss at 68 weeks including all patients 28.7% average weight loss among patients who stayed on treatment Some patients lost so much weight that they exited the trial voluntarily 84% of trial participants had severe obesity (BMI 35) Dr

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