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No receptor downregulation: Unlike some fat burners that lose effectiveness as your body adapts, AOD 9604 doesn't cause significant receptor desensitization

If you add B12 supplementation, space it at least 2 hours apart from any other medications or high-dose mineral supplements to avoid interference

This mechanism enhances fat metabolism and supports body composition improvement without affecting blood glucose, insulin sensitivity, or IGF-1 levels like full-length growth hormone would

High doses might also possibly interfere with levels of other vitamins, enzymes and minerals, which is always a potential problem when taking any nutrient in very large quantities