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Mercado, MD Jose A

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Available data suggest that under hypoxichypoglycemic conditions of ischemic stroke, oligodendrocytes are particularly vulnerable owing to their high iron load, low levels of reduced glutathione, elevated oxidative metabolic rate, abundant lipid and sphingolipid content, and the high permeability of their glutamate receptors (S

Ferroptosis inhibition by deferiprone, attenuates myelin damage and promotes neuroprotection in demyelinated optic nerve

Additionally, patients on chemotherapy should consult with their oncologist prior to using glutathione, as it may interfere with the oxidative stress mechanisms that some chemotherapeutic agents rely on to exert their cytotoxic effects