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Interstitial cystitis: In a trial of 12 women (ages 39-76) with moderate to severe interstitial cystitis unresponsive to conventional treatment, a single 10 mg BPC-157 injection led to complete symptom resolution in 10 patients and 80% improvement in 2, with no reported adverse effects (18) Knee pain: A retrospective study found that 11 of the 12 patients (91.6%) receiving BPC 157 as an intra-articular injection had significant improvement in knee pain, whereas 1 patient (8.3 %) had no improvement (19) Efficacy of BPC 157 Delivery Methods BPC-157 can be administered orally, topically, or via injection

BPC-157 (Body Protection Compound-157) is a 15-amino acid peptide with documented stability in gastric conditions and well-replicated effects on GI mucosal protection, tendon healing, and nitric oxide pathway modulation

Recent studies have revealed that the gut microbiota participates in the occurrence and development of AITD by influencing the gut-thyroid axis

Reasons for exclusion were: 1) the paper did not contain any relevant data

These are usually temporary and resolve with dose adjustment or switching to a different additive