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78 More recently, in the SURMOUNT-OSA trials, tirzepatide led to substantial weight loss and improved OSA severity, with BP effects that differed depending on concomitant continuous positive airway pressure use (7.6 mm Hg SBP and 2.8 mm Hg DBP reductions in nonusers versus 3.7 mm Hg and 1.1 mm Hg in users)

IGF-1 LR3 reduces the transport of glucose molecules into body cells, thus triggers the use of triglycerides or fat cells to synthesize energy for the body

Possible serious adverse reactions listed in the prescribing information for these medications include pancreatitis, gallbladder disease, hypoglycemia, kidney problems linked to dehydration, and severe gastrointestinal reactions

No shedding, irritation, or systemic side effects