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New data is regularly published, finding new or magnified benefits of GLP-1s

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LEADER, SUSTAIN-6, and REWIND trial outcomes The initial wave of cardiovascular outcome trials (CVOTs) predominantly focused on patients with type 2 diabetes at elevated cardiovascular risk

Whether this should be regarded as specific metabolic treatment, targeting only the metabolic alterations of the syndrome, is debatable, since the improvement in metabolic conditions, e.g., insulin resistance, would tenably have a positive impact also in gonadal function in women with PCOS