mthfr and semaglutide Additive hepatoprotective effects of resmetirom combination therapy in the GAN diet-induced obese and biopsy-confirmed mouse model of MASH Semaglutide and Genetics: Weight Management

Lovig KO, Horwitz L, Lipska K, Kosiborod M, Krumholz HM , Inzucchi SE

The FDA granted some significant approvals in 2024, including BMS Cobenfy for schizophrenia, Eli Lillys Kisunla for Alzheimers disease and Madrigal Pharmaceuticals Rezdiffra for metabolic dysfunction-associated steatohepatitis

Dal Negro, R., Turco, P., Pomari, C., and De Conti, F

The Precision Peptide Genetic Test analyzes 14 pathways, 49 peptides, 150+ genetic insights, including variants in FTO, GLP1R, MC4R, and TCF7L2 that shape baseline GLP-1 and energy-balance biology

Dietary changes : Patients starting GLP-1 therapy often make significant dietary modifications, including increased vegetable and fruit consumption (which have high water content) and reduced processed food intake