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Vitamin C (ascorbic acid): People who take high doses (reported at 12 or more tablets daily), tend to have lower levels of vitamin C, but not if also taking a vitamin C supplement (Sahud, Lancet 1971)

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ZIP7 resides on the ER membrane and releases zinc into the cytosol (following phosphorylation by CK2), thereby acting as a second messenger to activate signaling cascades such as AKT and ERK

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