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Most evidence is derived from animal models and limited human studies, and its mechanisms continue to be investigated

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The debilitating, slow damage created by high levels of blood sugar (glucose) destroys everything from your blood vessels to your eyes, kidneys, and nerves over time due to oxidative stress (remember the free radicals or reactive oxygen species (ROS)?)

The mechanism of gastric bypass surgery is to cause restriction by creating a smaller stomach pouch and then causing nutrient malabsorption by bypassing a portion of the stomach and small intestine