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Our studies indicated that EGF prevents acetaldehyde-induced disruption of tight junction and adherens junctions and reduce the paracellular permeability in Caco-2 cell monolayer by a phospholipase C, protein kinase C (PKC) and MAP kinase (MAPK)-dependent mechanisms (8183)

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The Morris water maze, a hippocampal-dependent spatial learning task requiring rats to locate a pedestal hidden beneath the surface of the water by orienting themselves to extra- maze cues was employed to evaluate the impact of the HGF antagonist, Hinge, on the pro- cognitive effects of Dihexa