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However, emerging evidence highlights the existence of a dynamic oral-gut axis, wherein oral microbes and their metabolites can translocate to the gastrointestinal tract, reshape gut microbial ecology, and impact host immunity and metabolism

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This article reports what has been documented, not what should be done

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Nat Methods 18(7):747756 Altaf MA, Shahid R, Ren MX, Altaf MM, Jahan MS, Khan LU (2021) Melatonin mitigates nickel toxicity by improving nutrient uptake fluxes, root architecture system, photosynthesis and antioxidant potential in tomato seedlings

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