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NAD+ supports deep cellular repair, energy production, and long-term resilience, while glutathione helps with detoxification, inflammation control, and antioxidant defence

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The central clinical idea: when mitochondrial ATP production falls and oxidative stress rises, the brain may lose the energy and antioxidant reserve needed to regulate neurotransmission, maintain cell membranes, recycle methionine, produce SAM, clear adenosine and homocysteine, build glutathione and tolerate medications or supplements

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