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If you stop using a GLP-1 medication, its common to regain some or all of the weight you lost, especially if lifestyle changes arent maintained

Compounded medications are not FDA-approved but may be prescribed when appropriate for individual patient needs

On semaglutide, where lean mass preservation is a meaningful concern during significant weight loss, cycling-only patients are at higher risk of losing muscle than those who combine cycling with resistance training

Unexpected population trends raise sustainability and disparity concerns Although GLP-1s are known to be effective in managing type 2 diabetes, the rapid rise of GLP-1s in recent years has been largely driven by its weight loss benefits

Many are inexpensive and widely available