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NGR-based strategies for targeting delivery of chemotherapeutics to tumor vasculature

Following importation across the plasma membrane by system Xc-, cys is promptly converted to cysteine, which is considered the limiting precursor of GSH synthesis

1 This was followed later in the year by the approval of another blood-based diagnostic test, this one designed for use in broader clinical settings

Option (Evidence Strength: Grades C, C, and B) Procedures Cystoscopy under anesthesia with short-duration, low-pressure hydrodistension may be undertaken as a treatment option

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