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The objective of this review is to provide a comprehensive and structured synthesis of the immunopathogenesis of HT, integrating established knowledge with emerging research areas including oxidative stress, gut microbiota, and epigenetic modifications, while also summarizing current clinical, diagnostic, and therapeutic perspectives (Fig

As mentioned earlier, specific expression of ER plays a role in the pathogenesis of PRLomas and could be used as a predictor for tumor aggressiveness and response to therapy

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