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Building upon this newly identified target-apoptosis axis, our findings extend the established pharmacological profile of palmatine , an isoquinoline alkaloid from Coptis chinensis and Phellodendron chinense with documented efficacy in MASLD 80

Bolanos, J

However, other factors may be involved, including accumulation of lactate, pyruvate, glutamine and free glucose, and depletion of glycogen, ketone bodies and glutamate

Dunker, C

However, within 1ns of MD simulation, it shifted to an adjacent site, remained there up to 140 ns, and after 140 ns completely dissociated from ChaC1 as evident from the sudden rise of RMSD of juglone (red line) with respect to the protein up to 18 as seen in figure 9 A