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This aging mechanism is closely related to various common diseases, including atherosclerosis, hypertension, chronic obstructive pulmonary disease, diabetes, and neurodegenerative disorders ( Current senolytic agents are primarily employed in cancer therapies, such as doxorubicin, trametinib, and cell cycle-targeting drugs like palbociclib ( Although studies have shown that FOXO4-DRI can block the binding of P53 to FOXO4, thereby promoting the apoptosis of senescent cells, the effect of FOXO4-DRI is not limited to alleviating the aging of certain organs

TB-500: Thymosin Beta-4 TB-500 is a synthetic version of thymosin beta-4, a naturally occurring peptide found in most animal and human cells

10.1080/09513590.2024.2302402 136 ZhuangC.LuoX.WangW.SunR.QiM.YuJ

Alcohol, Stress, and Inflammation Excess alcohol, chronic stress, and high inflammation can make it harder for the body to repair and respond