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Interestingly, and in contrast to colesevelam, liraglutide increased reabsorption of bile acids [assessed by 75-selenium homocholic acid taurine test (SeHCAT)] and decreased bile acid synthesis (assessed by circulating C4), possibly via a liraglutide-induced increase in FGF-19 secretion from enterocytes, thus rectifying core pathophysiological features of bile acid diarrhea
There are a few angles to consider: Improved Vascular Function: ED is largely a vascular issue
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Ex vivo human placental transfer of the peptides pramlintide and exenatide (synthetic exendin-4)
These medications carry a boxed warning and are contraindicated in patients with personal or family history of medullary thyroid carcinoma or MEN2 syndrome
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