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Glucagon-like peptide-1 (GLP-1) receptor agonists, originally developed for type 2 diabetes management, have emerged as a promising treatment for weight loss, with secondary benefits for OSA

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Weight Loss: Average weight loss in the LEAD trials was 2 kg to 3.24 kg, with the majority of the reduction noted in the first 4 months of therapy, but tending to be sustained throughout the remaining period of the studies

Baricitinib counteracts metaflammation, thus protecting against diet-induced metabolic abnormalities in mice