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Experiment with prescription topicals The last thing you may want to try before taking the plunge and starting isotretinoin are prescription topicals, which often work better to defeat acne on the skin than OTC products (but arent as strong and dont carry as many side effects as oral medications)

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The clinical consequences could range from local inflammation or rash through to serious health issues, such as systemic hypersensitivity, including anaphylaxis, or antibody formation

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