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Wegovy and Zepbound carry FDA approval for chronic weight management

Iwase T, Oveson BC, Hashida N, Lima e Silva R, Shen J, Krauss AH, Gale DC, Adamson P, Campochiaro PA

Stratified by CPAP use Subgroup analysis stratified by CPAP use revealed that GLP-1 RAs significantly reduced AHI regardless of whether participants were on CPAP therapy

doi: 10.1038/s41598-017-06237-5, 112 Wolfgang ViechtbauerN.CheungM

In T cells of SLE patients, mTOR activation triggers ROS production, while SIRT2 concurrently upregulates IL-17A expression in these cells by modulating the mTOR complex 1 (mTORC1)/HIF-1/RORt signaling pathway, thereby contributing to the pathogenesis of SLE (155)