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Risks include patchy skin color and potential premature graying of hair
Following a one week acclimatization period, the rats were randomly divided into five groups: H1 (control): No treatment., H2: Single dose of mercury (Hg) chloride (70 mg/kg) administered on the first day, H3: Continuous administration (every other day) of Hg chloride (2 mg/kg/day) for 4 weeks, H4: Single dose of Hg chloride (70 mg/kg) on the first day along with continuous administration (every other day) of N-acetylcysteine (NAC) (50 mg/kg/day) for 4 weeks, and H5: Continuous co-administration of Hg chloride (2 mg/kg/day) along with NAC (50 mg/kg/day) every other day for 4 weeks
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Store in clearly labeled vials with concentration and date of reconstitution noted
As an inducer of NRF2, DMF could promote SLC7A11 and GPX4 expression, increase cellular cystine and glutathione levels, and mediate anti-oxidative stress effects
