A wide range of nano-drug delivery systems (NDDS), including lipid nanoparticles, nanoliposomes, polymeric micelles, nanosuspensions, and self-microemulsifying systems, have been developed to enhance the pharmacokinetic stability and therapeutic efficacy of bioactive natural compounds (151)
doi: 10.3748/wjg.v23.i15.2771
When ERS occurs, GRP78 binds to misfolded proteins and dissociates from PERK, IRE1, and ATF6, activating downstream signaling pathways to inhibit DNA transcription and translation, prevent protein synthesis, and accelerate the degradation of aberrant proteins, thus regulating the adaptation of the intracellular environment
Microplastic in marine organism: environmental and toxicological effects
This formula combines resurfacing with regeneration