Beyond its primary indication in sleep, DSIP offers a cascade of secondary benefits, including stress reduction, pain relief, neuroprotection, and support in addiction recovery ( 4, 5, 6, 7 )
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Phase 2 trial (NEJM 2023) randomized 338 adults with obesity to retatrutide doses from 1 mg to 12 mg/week
However, the underlying mechanisms of pancreatic islet fibrosis and -cell failure remain unclear