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Table of Contents Jardiance (Empagliflozin) Product Category Diabetes & Heart Failure SGLT2 Inhibitor Generic Name or Biosimilar No Active Ingredient Empagliflozin Prescription Status Prescription-only Targeted Conditions Jardiance is approved to treat the following conditions: Type 2 Diabetes Mellitus (T2DM), to improve glycemic control Heart Failure with Reduced Ejection Fraction (HFrEF), to reduce the risk of cardiovascular death and hospitalization Chronic Kidney Disease (CKD), to slow progression and improve renal outcomes Off-Label Usage Some off-label uses being studied or prescribed include: Heart Failure with Preserved Ejection Fraction (now formally approved) Type 1 Diabetes (investigational

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Synergistic Benefits for Enhanced Health When these two medications are combined, their distinct mechanisms of action create a powerful synergy that can lead to superior outcomes: Superior Blood Glucose Control: Mounjaro tackles glucose control from various angles, from stimulating insulin release to slowing gastric emptying and suppressing appetite

Galectin-3 has been shown to be involved in pathological cardiac fibrosis and remodeling (Suthahar et al., 2018)