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By protecting these compounds from degradation and promoting controlled, targeted release, nano-delivery systems make these polyphenols more effective for use in health and disease management applications

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Antioxidant effects after coffee enema or oral coffee consumption in healthy Thai male volunteers S Teekachunhatean N Tosri C Sangdee R Wongpoomchai W Ruangyuttikarn C Puaninta S Srichairatanakool We designed an open-label, randomized two-phase crossover study to investigate the antioxidant effects after single and multiple doses of a coffee enema versus coffee consumed orally

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Often, oxidative stress sits at the center of that shift, and the effects can show up far beyond the mirror