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Specifically, Gclc ablation in FoB induces metabolic features of wild-type MZB such as increased ATP levels, glucose metabolism, mTOR activation, and protein synthesis

Use within 28 days of reconstitution, and discard the vial if the solution becomes cloudy, loses its blue tint, or develops particles

Based on domain architecture comparison with HNF4 58,59 , we engineered an NHR-49 truncation (295422) to disrupt ligand binding by removing a majority of the ligand binding domain, while retaining its analogous N-terminal, DNA-binding, hinge, and C-terminal domains (Fig

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Patients on high doses for extended periods should be monitored by their healthcare provider for signs of adrenal insufficiency