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Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and -synuclein

April 11th, 2025: Ozempic and the Evolving GLP-1 Drug Market: Pfizer Ends Danuglipron Development Pfizer has officially discontinued development of its experimental weight loss pill, danuglipron, following a case of liver enzyme elevation in a clinical trial

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Materials and Methods: This scoping review was conducted according to the Joanna Briggs Institute (JBI) methodology and summarised the published literature on the mechanisms of action of carnitine (s) that counteract the mechanisms of dioxin(s)-inducing MASLD/MDAFLD/NAFLD/NASH/ in the preclinical studies

Chen Y, Liu Y, Lan T, Qin W, Zhu YT, Qin K, Gao JJ, Wang HB, Hou XM, Chen N, Angeli JPF, Conrad M, Wang C