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They were provided either a placebo or a low or high dose of Amarasate the day of the fast

In the last step of the oxidative phase, ribulose 5-phosphate is converted to ribose 5-phosphate by the enzyme phosphopentose isomerase (Figure 4)

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Brain and nervous system: Inflammatory signaling can influence fatigue, mood, sleep, and pain sensitivity, but these symptoms are not specific to metabolic inflammation and have complex drivers