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Lysophosphatidylcholine (LPC)-induced demyelination A widely used model to study remyelination, involving injection of LPC to induce focal demyelination in either the corpus callosum or spinal cord, which is typically complete by 3 days after injection and is followed by robust remyelination without ongoing demyelination over the subsequent 24 weeks

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Plasma was separated from other blood components by centrifugation at 1200 g for 45 min at 10 C

PubMed Central , Free Radical Biology and Medicine , vol