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June 1, 2020
Either the mouse chimeric version of r84/PGN311 (mcr84, red line) or control (Control, black line) antibody was administered via i.p
Glucagon-like peptide-1 increases heart rate by a direct action on the sinus node
Disclosures: Loghman Salimzadeh: Nothing to Disclose, Stuti Shah: Nothing to Disclose, Danie La: Nothing to Disclose, Hilario Ramos: Bluejay Therapeutics: Employee, Bluejay Therapeutics: Stock privately held company, Nancy Shulman: Bluejay Therapeutics, INC: Salary and equity, Hassan Javanbakht: Nothing to Disclose, Adam Gehring: Nothing to Disclose 452 PRECLINICAL PHARMACOKINETICS OF EDP-514, AN ORAL, ONCE-DAILY ANTIVIRAL TREATMENT FOR HEPATITIS B VIRUS Meng Huang 1 Khanh Hoang 1 Jonathan Kibel 1 Shucha Zhang 1 Lisha Xu 1 Yang Li 1 Indy Zang 1 Daniel Leonard 1 Siu-Lung Chan 1 Joshua Klaene 1 Yat Sun Or 1 Li-Juan Jiang 1 , 1 Enanta Pharmaceuticals Background: Hepatitis B virus (HBV) is a global public health threat that causes approximately 1.5 million new infections every year