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In this regard, it is interesting that IgG antibodies that show similar FcRn binding properties can have variable plasma half-lives due to differences in biophysical properties, such as pI and net charge, which affect cellular handling 83,84,85,86,87

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Glucagon-like peptide-1 receptor agonists and risk of parkinsons disease in patients with type 2 diabetes: a population-based cohort study

Reducing that frequency could be a competitive advantage against similarly-dosed rivals like Eli Lilly's tirzepatide-based Mounjaro and Zepbound, help patients comply with treatment, and potentially reduce the cost of therapy