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Both medications can cause tiredness, though through different mechanisms

Recycles other antioxidants: Once Vitamin C and Vitamin E do their job, glutathione helps restore them so they can work again

Mochida Y, Taguchi K, Taniguchi S, Tsuneyoshi M, Kuwano H, Tsuzuki T et al (2003) The role of P-glycoprotein in intestinal tumorigenesis, disruption of mdr1a suppresses polyp formation in Apc(Min/+) mice