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[DOI] [PMC free article] [PubMed] [Google Scholar] 30.Page M.J., McKenzie J.E., Bossuyt P.M., Boutron I., Hoffmann T.C., Mulrow C.D., Shamseer L., Tetzlaff J.M., Akl E.A., Brennan S.E., et al

There are many types of laxatives , ranging from those that: Help soften hard stools by drawing water in Lubricate the stools and intestinal lining for easier passage Stimulate intestinal muscle contractions to push stool through the digestive tract Stimulant laxatives in particular should be used sparingly and for short-term relief only, unless directed by a healthcare professional

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Clinical trials of semaglutide have reported cases of acute pancreatitis, though the incidence rates remain relatively low