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Researchers identified that certain fragments of -MSH exhibited potent beneficial properties, even in isolation from the full hormone

Long-term deficiency can lead to serious heart and neurological problems

Absorption can be reduced by age, gut health, GI surgery, or medications, making direct delivery methods more reliable for restoring function

Adults can completely fail to absorb the vitamin administered orally

The NHS Inform Scotland guidance and the Vegan Societys recommendation align: a 10-microgram daily B12 supplement, or a 2,000-microgram weekly supplement, is enough for the vast majority of plant-based eaters