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Doubling up to 'catch up' creates unnecessary gastrointestinal stress without proportional therapeutic benefit, as glutathione absorption is dose-limited by intestinal transport capacity (approximately 200300mg per administration for oral forms)

The final reconstituted solution must be roughly isotonic that is, it should have appropriate salt content because bacteriostatic water alone is hypotonic

However, gene therapy offers new avenues to address underlying pathology

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